Läste lite igår om t-celler och covid 19.
Having a range of immune cells that target different parts of the virus appears to make disease milder and could protect against future variants.
theconversation.com
”Many of the vaccines designed to date – including Moderna’s, Pfizer’s and AstraZeneca’s – have focused on just one major target on the coronavirus: its spike protein. These vaccines have been tremendously effective at generating antibodies. They also stimulate a T cell response to the spike.
But now that we understand more about the role of T cells, the importance of having a broad T cell response, and the issue of antibodies waning, perhaps we should consider refocusing our vaccine strategies on generating T cells and on targeting more than just one protein.”
Sedan läste jag det här med t cellerna:
The immune systems of more than 95% of people who recovered from COVID-19 had durable memories of the virus up to eight months after infection.
www.nih.gov
”Levels of T cells for the virus also remained high after infection. Six months after symptom onset, 92% of participants had CD4+ T cells that recognized the virus. These cells help coordinate the immune response. About half the participants had CD8+ T cells, which kill cells that are infected by the virus.
Hittade en svensk studie om naturligt t-cells skydd bland ovaccinerade som man gjort. Verkar som om 55% av testgruppen utvecklade t-celler mot Covid 19.
Researchers at Karolinska Institutet have analysed the presence of SARS-CoV-2-specific antibodies and memory cells of the immune system in young adults. The results, published in The Journal of Allergy and Clinical Immunology, show that over one in four had antibodies due to the infection. Fewer...
news.ki.se
”In more than 100 participants, researchers also measured the levels of SARS-CoV-2 specific memory cells, which can be activated if the virus re-enters the body. Among those who tested positive for antibodies, 70 percent had detectable levels of memory B cells (the cells that make antibodies), while 55 percent had memory T cells. These proportions are lower than previously reported in studies on other populations, where measurable levels of memory cells have been found in most people infected with SARS-CoV-2.”